Martin-Luther-Universität Halle-Wittenberg

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Scopus Author ID 16645270900
ResearcherID C-6596-2009
ORCID ID 0000-0002-3272-1721

Originalarbeiten

2018

47. Lysine-based amino-functionalized lipids for gene transfection: the influence of chain composition on 3D phase behaviour and transfection performance. S. Tassler, D. Pawlowska, C. Janich, J. Giselbrecht, S. Drescher, A. Langner, C. Wölk, and G. Brezesinski, Phys. Chem. Chem. Phys. 2018, 20, 17393-17405. [LINK]   

46. Mixing behaviour of asymmetrical glycerol diether bolalipids wit saturated and unsaturated phosphatidylcholines. S. Müller, A. Meister, C. Otto, G. Hause, and S. Drescher, Biophys. Chem. 2018, 238, 39-48. [LINK]   

45. Impact of Headgroup Asymmetry and Protonation State on the Aggregation Behavior of a New Type of Glycerol Diether Bolalipid. S. Drescher, C. Otto, S. Müller, V.M. Garamus, C.J. Garvey, S. Grünert, A. Lischka, A. Meister, A. Blume, and B. Dobner, Langmuir 2018, 34, 4360-4373. [LINK]   

44. Synthesis and aggregation behaviour of single-chain, 1,32-alkyl branched bis(phosphocholines): effect of lateral chain length. K. Gruhle, S. Müller, A. Meister, and S. Drescher, Org. Biomol. Chem. 2018, 16, 2711-2724. [LINK]   

2016/2017

43. An Asymmetrical Glycerol Diether Bolalipid with Protonable Phosphodimethylethanolamine Headgroup: The impact of pH on Aggregation Behavior and Miscibility with DPPC. T. Markowski, S. Müller, B. Dobner, A. Meister, A. Blume, and S. Drescher, Polymers 2017, 9, 573. [LINK]   

42. Azide-modified Membrane Lipids: Synthesis, Properties, and Reactivity. S. Lindner, K. Gruhle, R. Schwarz, V.M. Garamus, D. Ramsbeck, G. Hause, A. Meister, A. Sinz, and S. Drescher, Langmuir 2017, 33, 4960-4973. [LINK]   

41. Aggregation behaviour of a single-chain, phenylene-modified bolalipid and its miscibility with classical phospholipids. S. Drescher, V.M. Garamus, C.J. Garvey, A. Meister, and A. Blume, Beilstein J. Org. Chem. 2017, 13, 995-1007. [LINK]   

40. The cmc-value of a bolalipid with two phosphocholine headgroups and a C24 alkyl chain: Unusual binding properties of fluorescence probes to bolalipid aggregates. M. Kordts, A. Kerth, S. Drescher, M. Ott, and A. Blume, J. Colloid Interf. Sci. 2017, 501, 294-303. [LINK]   

39. Synthesis and EPR-spectroscopic characterization of the perchlorotriarylmethyl tricarboxylic acid radical (PTMTC) and its 13C labelled analogue (13C-PTMTC). M. Elewa, N. Maltar-Strmecki, M.M. Said, H.A. El Shihawy, M. El-Sadek, J. Frank, S. Drescher, M. Drescher, K. Mäder, D. Hinderberger, and P. Imming, Phys. Chem. Chem. Phys. 2017, 19, 6688-6697. [LINK]   

2014/2015

38. Investigation of Binary Lipid Mixtures of a Three-Chain Cationic Lipid with Phospholipids Suitable for Gene Delivery. C. Wölk, C. Janich, A. Meister, S. Drescher, A. Langner, G. Brezesinski, and U. Bakowsky, Bioconjugate Chem. 2015, 26, 2461-2473. [LINK]   

37. Injectable LiNc-BuO loaded microspheres as in vivo EPR oxygen sensors after co-implantation with tumor cells. J. Frank, D. Gündel, S. Drescher, O. Thews, and K. Mäder, Free Rad. Bio. Med. 2015, 89, 741-749. [LINK]   

36. Highly asymmetrical glycerol diether bolalipids: synthesis and temperature-dependent aggregation behavior T. Markowski, S. Drescher, G. Förster, B.-D. Lechner, A. Meister, A. Blume, and B. Dobner, Langmuir 2015, 31, 10683-10692. [LINK]   

35. Tris(2-aminoethyl)amine-based alpha-Branched Fatty Acid Amides – Synthesis of Lipids and Comparative Study of Transfection Efficiency of their Lipid Formulations. N. Erdmann, C. Wölk, I. Schulze, C. Janich, M. Folz, S. Drescher, M. Dittrich, A. Meister, J. Vogel, T. Groth, B. Dobner, and A. Langner, Eur. J. Pharm. Biopharm. 2015, 96, 349-362. [LINK]   

34. Synthesis, characterization, and nanoencapsulation of tetrathiatriarylmethyl and tetrachlorotriarylmethyl (trityl) radical derivatives – a study to advance their applicability as in vivo EPR oxygen sensors. J. Frank, M. Elewa, M.M. Said, H.A. Elshihawy, M. El-Sadek, D. Müller, A. Meister, G. Hause, S. Drescher, H. Metz, P. Imming, and K. Mäder, J. Org. Chem. 2015, 80, 6754-6766. [LINK]   

33. Lamellar versus Micellar Structures – Aggregation Behavior of a Triple-Chain Cationic Lipid Designed for the Non-viral Polynucleotide Transfer. C. Wölk, C. Janich, D. Pawlowska, S. Drescher, A. Meister, G. Hause, B. Dobner, A. Langner, and G. Brezesinski, ChemPhysChem 2015, 16, 2115-2126. [LINK]   , Cover Picture: ChemPhysChem 2015, 16, 2029. [LINK]   

32. Phenylene bolaamphiphiles: Influence of the substitution pattern on the aggregation behavior and the miscibility with classical phospholipids. S. Drescher, A. Meister, V.M. Garamus, G. Hause, C.J. Garvey, B. Dobner, and A. Blume, Eur. J. Lipid Sci. Technol. 2014, 116, 1205-1216. [LINK]   

31. The headgroup (a)symmetry strongly determines the aggregation behavior of single-chain phenylene-modified bolalipids and their miscibility with classical phospholipids. S. Drescher, B.-D. Lechner, V.M. Garamus, L. Almásy, A. Meister, and A. Blume, Langmuir 2014, 30, 9273-9284. [LINK]   

30. Composites of Malonic Acid Diamides and Phospholipids – Structural Parameters for Optimal Transfection Efficiency in A549 Cells. C. Janich, C. Wölk, S. Tassler, S. Drescher, A. Meister, G. Brezesinski, B. Dobner, and A. Langner, Eur. J. Lipid Sci. Technol. 2014, 116, 1184-1194. [LINK]   

29. New Micellar Transfection Agents. C. Wölk, D. Pawlowska, S. Drescher, A. Auerswald, A. Meister, G. Hause, A. Blume, A. Langner, G. Brezesinski, and B. Dobner, Langmuir 2014, 30, 4905-4915. [LINK]    

28. Structure-properties relationships in a series of diglycerol tetraether
model lipids and their lyotropic assemblies: Effect of branching topology
and chirality. T. Markowski, S. Drescher, A. Meister, A. Blume, and B. Dobner, Org. Biomol. Chem. 2014, 12, 3649-3662. [LINK]   

27. Self-assembly of different single-chain bolaphospholipids and their miscibility with phospholipids or classical amphiphiles. A. Blume, S. Drescher, G. Graf, K. Köhler, and A. Meister, Adv. Colloid Interf. Sci. 2014, 208, 264-278. [LINK]   

26. Synthesis of novel asymmetrical single-chain phosphoglycol-based bolaamphiphiles. S. Drescher and B. Dobner, Synthetic Commun. 2014, 44, 564-573. [LINK]   

2012/2013

25. Tuning the Aggregation Behaviour of Single-Chain Bolaamphiphiles in Aqueous Suspension by Changes in Headgroup Asymmetry. G. Graf, S. Drescher, A. Meister, V.M. Garamus, B. Dobner, and A. Blume, Soft Matter 2013, 9, 9562-9571. [LINK]    

24. General Synthesis and Physico-Chemical Characterisation of a Series of Peptide-Mimic Lysine-Based Amino-Functionalised Lipids. C. Wölk, S. Drescher, A. Meister, A. Blume, A. Langner, and B. Dobner, Chem. Eur. J. 2013, 19, 12824-12838. [LINK]    

23. Tuning the Aggregation Behaviour of Single-Chain Bolaphospholipids in Aqueous Suspension: From Nanoparticles to Nanofibres to Lamellar Phases. A. Blume, S. Drescher, A. Meister, G. Graf, and B. Dobner, Faraday Discuss. 2013, 161, 193-213. [LINK]    

22. Bolalipid fiber aggregation can be modulated by the introduction of sulfur atoms into the spacer chain. G. Graf, S. Drescher, A. Meister, V.M. Garamus, B. Dobner, and A. Blume, J. Colloid Interf. Sci. 2013, 393, 143-150. [LINK]    

21. Synthesis of symmetrical, single-chain, phenylene/biphenylene-modified bolaamphiphiles. S. Drescher, S. Sonnenberger, A. Meister, A. Blume, and B. Dobner, Monatsh. Chemie 2012, 143(11), 1533-1543. [LINK]    

20. Functionalization of Bolalipid Nanofibers by Silicification and Subsequent One-Dimensional Fixation of Gold Nanoparticles. S. Drescher, G. Hempel, W.H. Binder, B. Dobner, A. Blume, and A. Meister, Langmuir 2012, 28, 11615-11624. [LINK]    

19. Bis-Sonogashira Cross-Coupling: An Expeditious Approach towards Long-Chain, Phenylene-Modified 1,omega-Diols. S. Drescher, S. Becker, B. Dobner, and A. Blume, RSC Adv. 2012, 2, 4052-4054. [LINK]    

2010/2011

18. Self-Assembled Bolaamphiphile Fibers have Intermediate Properties between Crystalline Nanofibers and Wormlike Micelles: Formation of Viscoelastic Hydrogels Switchable by Changes in pH and Salinity. G. Graf, S. Drescher, A. Meister, B. Dobner, and A. Blume, J. Phys. Chem. B 2011, 115, 10478-10487. [LINK]    

17. Synthesis of Optical Pure Diglyceroltetraether Model Lipids with Non-Natural Branching Pattern. T. Markowski, S. Drescher, A. Meister, G. Hause, A. Blume, and B. Dobner, Eur. J. Org. Chem. 2011, 5894-5904. [LINK]    

16. Water Dynamics in Bolaamphiphile Hydrogels Investigated by 1H-NMR Relaxometry and Diffusometry. M. Bastrop, A. Meister, H. Metz, S. Drescher, B. Dobner, K. Mäder, and A. Blume, J. Phys. Chem. B 2011, 115, 14-22. [LINK]    

15. Formation of Square Lamellae by Self-Assembly of Long-Chain Bolaphospholipids in Water. A. Meister, S. Drescher, G. Karlsson, G. Hause, U. Baumeister, G. Hempel, V.M. Garamus, B. Dobner, and A. Blume, Soft Matter 2010, 6, 1317-1324. [LINK]    

14. Synthesis of novel symmetrical, single-chain, diacetylene-modified bolaamphiphiles with different alkyl chain lengths. S. Drescher, K. Helmis, A. Langner, and B. Dobner, Monatsh. Chemie 2010, 141, 339-349. [LINK]    

13. Amino-Functionalized Single-Chain Bolalipids: Synthesis and Aggregation Behavior of New Basic Building Blocks. S. Drescher, G. Graf, G. Hause, B. Dobner, and A. Meister, Biophys. Chem. 2010, 150, 136-143. [LINK]    

2005-2009

12. The motional dynamics in bolaamphiphile nanofibers and micellar aggregates: An ESR spin probe study. M. Bastrop, A. Meister, H. Metz, S. Drescher, B. Dobner, K. Mäder, and A. Blume, J. Phys. Chem. B 2009, 113, 574-582. [LINK]    

11. General Synthesis and Aggregation Behaviour of Novel Single-chain Bolaphospholipids: Variations in Chain and Headgroup Structures. S. Drescher, A. Meister, G. Graf, G. Hause, A. Blume, and B. Dobner, Chem. Eur. J. 2008, 14, 6796-6804. [LINK]   

10. Temperature-dependent Self-assembly and Mixing Behavior of Symmetrical Single-chain Bolaamphiphiles. A. Meister, S. Drescher, V.M. Garamus, G. Karlsson, G. Graf, B. Dobner, and A. Blume, Langmuir 2008, 24, 6238-6246. [LINK]   

9. Helical Nanofibers of Self-Assembled Bipolar Phospholipids as Template for Gold Nanoparticles. A. Meister, S. Drescher, I. Mey, M. Wahab, G. Graf, V.M. Garamus, G. Hause, H.-J. Mögel, A. Janshoff, B. Dobner, and A. Blume, J. Phys. Chem. B 2008, 112, 4506-4511. [LINK]   

8. Mixing Behavior of a Symmetrical Single-Chain Bolaamphiphile with Phospholipids. A. Meister, K. Köhler, S. Drescher, B. Dobner, G. Karlsson, K. Edwards, G. Hause, and A. Blume, Soft Matter 2007, 3, 1025-1031. [LINK]   

7. Structure-Property Relationship in Stimulus-Responsive Bolaamphiphile Hydrogels. A. Meister, M. Bastrop, S. Koschoreck, V.M. Garamus, T. Sinemus, G. Hempel, S. Drescher, B. Dobner, W. Richtering, K. Huber, and A. Blume, Langmuir 2007, 23, 7715-7723. [LINK]   

6. Evidence for a Reverse U-Shaped Conformation of Single-Chain Bolaamphiphiles at the Air-Water Interface. A. Meister, M.J. Weygand, G. Brezesinski, A. Kerth, S. Drescher, B. Dobner, and A. Blume, Langmuir 2007, 23, 6063-6069. [LINK]   

5. General Synthesis and Aggregation Behaviour of a Series of Single-chain 1,omega-Bis(phosphocholines). S. Drescher, A. Meister, A. Blume, G. Karlsson, M. Almgren, and B. Dobner, Chem. Eur. J. 2007, 13, 5300-5307. [LINK]   

4. Selective Nucleophilic Substitution Reactions in 2,4,6-Trisulfanyl-substituted Pyrimidin-5-carbonitriles by Secondary Amines. S. Drescher, D. Ramsbeck, D. Briel, and B. Dobner, J. Het. Chem. 2007, 44, 757-763. [LINK]   

3. Temperature-Dependent Aggregation Behavior of Symmetric Long-Chain Bolaamphiphiles at the Air-Water Interface. K. Köhler, A. Meister, B. Dobner, S. Drescher, F. Ziethe, and A. Blume, Langmuir 2006, 22, 2668-2675. [LINK]   

2. Conformational and thermal behavior of a pH-sensitive bolaform hydrogelator. K. Köhler, A. Meister, G. Förster, B. Dobner, S. Drescher, F. Ziethe, W. Richter, F. Steininger, M. Drechsler, G. Hause, and A. Blume, Soft Matter 2006, 2, 77-86. [LINK]   

1. Selective Nucleophilic Replacement of the Benzylsulfanyl Group in 2,4-Disulfanyl-substituted Thieno[2.3-d]pyrimidin-6-carboxylic Acid Derivatives by Secondary Amines. D. Briel, S. Drescher, and B. Dobner, J. Het. Chem. 2005, 42, 841-846. [LINK]   

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