Publications Dr. P. Frohberg
J. Pettelkau, Ch. H. Ihling, P. Frohberg, L. van Werven, O. Jahn, und A. Sinz: Reliable Identification of Cross-Linked Products in Protein Interaction Studies by C-13-Labeled p-Benzoylphenylalanin. J. Am. Soc. Mass Spectrom. 2014, 25, 1628-1641. [more]
P. Frohberg, I. Schulze, Ch. Donner, F. Krauth:
Remarkable stereoselectivity switch in synthesis of carbonyl substituted N2-arylamidrazones with low lipophilicity.
Tetrahedron Lett. 2012, 53, 4507-4509. [more]
F. Krauth, H.M. Dahse, H.H. Ruettinger, P. Frohberg:
Synthesis and characterization of novel 1,2,4-triazine derivatives with antiproliferative activity.
Bioorg. Med. Chem. 2010, 18, 1816-1821. [more]
F. Krauth, R. Friedemann, H.H. Ruettinger, P. Frohberg:
Open-chain and cyclic amidrazones forming persistent radicals. An electrochemical and quantum chemical study.
ARKIVOC 2009, (vii), 150-164. [more]
K. Abouzid, P. Frohberg, J. Lehmann, M. Decker:
6-Aryl-4-oxohexanoic acids: Synthesis, effects on eicosanoid biosynthesis, and anti-inflammatory in vivo-activities.
Med. Chem. 2007, 3, 433-438. [more]
P. Frohberg, G. Drutkowski, I. Wobst:
Monitoring eicosanoid biosynthesis via lipoxygenase and cyclooxygenase pathways in human whole blood by single HPLC run.
J. Pharmaceut. Biomed. Anal. 2006, 41, 1317-1324. [more]
P. Frohberg, Ch. Wagner, R. Meier, W. Sippl:
Derivatives of arylhydrazonic acids. Part 3: Stereochemical rearrangement of Z-oxanilo-N 1-dialkyl-N 2-arylamidrazones.
Tetrahedron 2006, 62, 6050-6060. [more]
I. Schaeffner, J. Petters, H. Aurich H, P. Frohberg, B. Christ:
A microtiterplate-based screening assay to assess diverse effects on cytochrome P450 enzyme activities in primary rat hepatocytes by various compounds.
Assay Drug Dev. Technol. 2005, 3, 27-38. [more]
K. Gorlitzer, B. Gabriel, P. Frohberg, I. Wobst, G. Drutkowski, J. Wiesner, H. Jomaa:
Thieno[2,3-c]quinolines - synthesis and biological investigation.
PHARMAZIE 2004,59, 439-442. [more]
K. Gorlitzer, M. Bode, P. Frohberg, G. Drutkowski:
Benzo[c][2,7]naphthyridines from 2,6-dinor-nifedipine and its dimethyll 2,5-dicarboxylate isomer.
PHARMAZIE 2004, 59, 15-20. [more]
K. Gorlitzer, J. Trittmacher, P.G. Jones, P. Frohberg, G. Drutkowski:
Isomeric phenanthridine from 1,2-dihydro-5-methyl-2'-nitro-[1,1'-biphenyl]2,6-dicarboxylic esters.
PHARMAZIE 2003, 58, 776-787. [more]
K. Gorlitzer, J. Trittmacher, P.G. Jones, P. Frohberg, G. Drutkowski:
Pyrano[3,4-c]quinolines from 1-desaza-1-oxa-nifedipine.
PHARMAZIE 2003, 58, 539-542. [more]
K. Gorlitzer, J. Fabian, P.G. Jones, P. Frohberg, G. Drutkowski:
Pyridazino[3,4-c]quinolines and pyridazino[4,5-c]quinolines - synthesis and investigation of lipoxygenase inhibition.
Pharmazie 2002, 57, 362-371.
G. Drutkowski, Ch. Donner, I. Schulze, P. Frohberg:
Derivatives of arylhydrazonic acids. Part 2: A facile approach to novel 4,5-dihydro-1H-1,2,4-triazoles via cyclization of amidrazones.
Tetrahedron 2002, 58, 5317-5326. [more]
P. Frohberg, G. Drutkowski, Ch. Wagner:
Derivatives of arylhydrazonic acids, 1 Synthesis and structural assignment of oxanilo-N-arylhydrazonoyl chlorides.
Eur. J. Org. Chem. 2002, 10, 1654-1663. [more]
K. Gorlitzer, J. Fabian, P. Frohberg, G. Drutkowski:
Pyrrolo[2,3-c]quinolines and pyrrolo[3,4-c]quinolines - synthesis and investigation of lipoxygenase inhibition.
Pharmazie 2002, 57, 243-247.
K. Gorlitzer, J. Fabian, P.G. Jones, P. Frohberg, G. Drutkowski:
Furo[2,3-c]quinolines and furo[3,4-c]quinolines - synthesis and investigation of lipoxygenase inhibition.
Pharmazie 2002, 57, 159-168.
P. Frohberg, G. Drutkowski, Ch. Wagner, O. Lichtenberger:
Journal of Chemical Structure elucidation of N-aryl-2-chloro-3-oxobutanamides with respect to intra- and intermolecular hydrogen bonding.
J. Chem. Res.-S. 2002, 1, 13-14. [more]
F. Clemens, G. Drutkowski, M. Wiese, P. Frohberg:
The inactivation of lipoxygenase-1 from soybeans by amidrazones.
Biochimica et Biophysica Acta (2001), 1549(1), 88-98. [more]
R. Fleischer, P. Frohberg, A. Buge, P. Nuhn, M. Wiese:
QSAR analysis of substituted 2-phenylhydrazonoacetamides acting as inhibitors of 15-lipoxygenase.
Quant. Struct.-Act. Relat. 2000, 19, 162-172. [more]
P. Frohberg, M. Wiese, P. Nuhn:
Lipoxygenase inhibitors. Part 6. Synthesis of new tetrahydropyrazine and other heterocyclic compounds by reaction of hydrazonoyl chlorides.
Arch. Pharm. Pharm. Med. Chem. 1997, 330, 47-52. [more]
P. Frohberg, U. Baumeister, D. Stroehl, H. Danz:
Study of tautomeric and isomeric behavior of new 2-arylhydrazono-1,4-benzothiazines.
Heterocycles 1997, 45, 1183-1190. [more]
P. Frohberg, P. Nuhn:
New synthesis of benzotriazepines by non-convenient cyclization reaction of N2,N3-diarylamidrazones.
Heterocycles 1996, 43, 2549-2552. [more]
P. Frohberg, C. Kupfer, P. Stenger, U. Baumeister, P. Nuhn:
Lipoxygenase inhibitors. IV: Synthesis and cyclization reactions of open-chain N1-aryl-substituted amidrazones.
Arch. Pharm. Pharm. Med. Chem. 1995, 328, 505-516. [more]
P. Frohberg, C. Kupfer, P. Nuhn:
P57 Lipoxygenase inhibiting amidrazones-reaction to 1,3,4-benzotriazepines.
Eur. J. Pharmaceut. Sci. 1994, 2, 133. [more]