Martin-Luther-Universität Halle-Wittenberg


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Ausgewählte Publikationen

Benndorf RA. Better blood flow delivered: extracellular matrix-derived hydrogels for the induction of arteriogenesis in peripheral artery disease? JACC: Basic to Translational Science. 2016, in press.

Ripperger A, Benndorf RA. The C421A (Q141K) polymorphism enhances the 3`-UTR-dependent regulation of ATP-binding cassette transporter ABCG2. Biochem Pharmacol. 2016, in press.

Widder M, Lützkendorf J, Caysa H, Unverzagt S, Wickenhauser C, Benndorf RA, Schmoll HJ, Müller-Tidow C, Müller T, Müller LP. Multipotent mesenchymal stromal cells promote tumor growth in distinct colorectal cancer cells by a β1-integrin-dependent mechanism. Int J Cancer. 2016; 138(4):964-75.

Flöther L, Raspé C, Bucher M, Benndorf RA. Multimodal pain management in a patient with atypical cervicogenic headache. Med Monatsschr Pharm. 2015; 38:448-50.

Bauer J, Ripperger A, Frantz S, Ergün S, Schwedhelm E, Benndorf RA. Pathophysiology of isoprostanes in the cardiovascular system: implications of isoprostane-mediated thromboxane A2 receptor activation. Br J Pharmacol. 2014; 171:3115-31.

Deppe S, Ripperger A, Weiss J, Ergün S, Benndorf RA. Impact of genetic variability in the ABCG2 gene on ABCG2 expression, function, and interaction with AT1 receptor antagonist telmisartan. Biochem Biophys Res Commun. 2014; S0006-291X: 02190-6.

Krebs CF, Lange S, Niemann G, Rosendahl A, Lehners A, Meyer-Schwesinger C, Stahl RA, Benndorf RA, Velden J, Paust HJ, Panzer U, Ehmke H, Wenzel UO. Deficiency of the Interleukin 17/23 Axis Accelerates Renal Injury in Mice With Deoxycorticosterone Acetate+Angiotensin II-Induced Hypertension. Hypertension. 2014; 63:565-71.

Najjar SM, Ledford KJ, Abdallah SL, Paus A, Russo L, Kaw MK, Ramakrishnan SK, Muturi HT, Raphael CK, Lester SG, Heinrich G, Pierre SV, Benndorf R, Kleff V, Jaffa AA, Lévy E, Vazquez G, Goldberg IJ, Beauchemin N, Scalia R, Ergün S. Ceacam1 deletion causes vascular alterations in large vessels. Am J Physiol Endocrinol Metab. 2013; 305:E519-29.

Choe CU, Atzler D, Wild PS, Carter AM, Böger RH, Ojeda F, Simova O, Stockebrand M, Lackner K, Nabuurs C, Marescau B, Streichert T, Müller C, Lüneburg N, Benndorf RA, Baldus S, Gerloff C, Blankenberg S, Heerschap A, Grant PJ, Magnus T, Zeller T, Isbrandt D, Schwedhelm E. Homoarginine levels are regulated by L-arginine:glycine amidinotransferase and affect stroke outcome: results from humans and mice. Circulation. 2013; 128:1451-61.

Editorial: Michel T. Circulation. 2013; 128:1400-4.

Biermann D,  Heilmann A, Didié M, Schlossarek S, Wahab A,  Grimm M, Reichenspurner H, Sultan KR, Steenpass A, Ergün S, Donzelli S Carrier L, Ehmke H, Zimmermann WH, Hein L, Böger RH, Benndorf RA. Impact of AT2 Receptor Deficiency on Postnatal Cardiovascular Development. PLoS ONE. 2012; 7:e47916.

Deppe S, Böger RH, Weiss J, Benndorf RA. Telmisartan: a review of its pharmacodynamic and pharmacokinetic properties. Expert Opin Drug Metab Toxicol. 2010; 6:863-71.

Wenzel UO, Krebs C, Benndorf RA. Role of the AT2 receptor in renal disease. J Renin Angiotensin Aldosterone Syst. 2010; 11:37-41.

Weiss J, Sauer A, Divac N, Storch CH, Schwedhelm E, Boger RH, Haefeli WE, Benndorf RA. Interaction of angiotensin receptor type 1 blockers with ATP-binding cassette transporters. Biopharm Drug Dispos. 2010; 31:150-61.

Weiss J, Sauer A, Herzog M, Boger RH, Haefeli WE, Benndorf RA. Interaction of thiazolidinediones with the ATP-binding cassette transporters P-glycoprotein and breast cancer resistance protein. Pharmacology. 2009; 84:264-70.

Böger RH, Sullivan LM, Schwedhelm E, Wang TJ, Maas R, Benjamin EJ, Schulze F, Levy D, Benndorf RA, Selhub J, Jacques P, Vasan RS. Association of plasma asymmetric dimethylarginine (ADMA) with mortality and cardiovascular disease in the community. Circulation. 2009; 119:1592-600.

Maas R, Xanthakis V, Polak J, Schwedhelm E, Wolf PA, Sullivan LM, Benndorf RA, Böger RH, Seshadri S, Vasan RS. Association of the endogenous nitric oxide synthase inhibitor ADMA with carotid artery intimal media thickness in the Framingham Heart Study offspring cohort. Stroke. 2009; 40:2715-9.

Schwedhelm E, Xanthakis V, Maas R, Sullivan LM, Schulze F, Riederer U, Benndorf RA, Böger RH, and Vasan RS. Asymmetric dimethylarginine reference intervals determined with tandem mass spectrometry-liquid chromatography: results from the Framingham Heart Study offspring cohort. Clin Chem. 2009; 55:1539-45.

Lieb W, Benndorf RA, Benjamin EJ, Sullivan LM, Maas R, Xanthakis V, Schwedhelm E, Aragam J, Schulze F, Böger RH, Vasan RS. Plasma asymmetric dimethylarginine, L-arginine and left ventricular structure and function in a community-based sample. Atherosclerosis. 2009; 204:282-7.

Benndorf RA, Krebs C, Hirsch-Hoffmann B, Schwedhelm E, Cieslar G, Schmidt Haupt R, Steinmetz O, Meyer-Schwesinger C, Thaiss F, Haddad M, Fehr S, Heilmann A, Helmchen U, Hein L, Ehmke H, Stahl R, Böger RH, Wenzel UO. Angiotensin II type 2 receptor deficiency is associated with increased morbidity and mortality in a mouse model of chronic renal failure. Kidney Int. 2009; 75:1039-49.

Editorial: Griffin KA und Bidani AK. Kidney Int. 2009; 75:1006-1008.

Benndorf RA, Schwedhelm E, Gnann A, Kom G, Heilmann A, Steenpass A, Ergün S, Böger RH. Isoprostanes inhibit VEGF-induced endothelial cell migration, tube formation, and cardiac vessel sprouting via activation of the thromboxane A2 receptor: a potential link between oxidative stress and impaired angiogenesis. Circ Res. 2008; 103:1037-46.

Editorial: Sauer H und Wartenberg M. Circ Res. 2008; 103:907-9.

Benndorf RA und Böger RH. Pleiotropic effects of telmisartan – still more to come? J Hypertens. 2008; 26:854-6.

Benndorf RA, Gehling UM, Appel D, Maas R, Schwedhelm E, Silberhorn E, Schlagner K, Hossfeld DK, Rogiers X, Böger RH. Mobilization of putative high proliferative potential-endothelial colony-forming cells during antihypertensive treatment in patients with essential hypertension. Stem Cells Dev. 2007; 16:329-38.

Bajcetic M, Benndorf RA#, Appel D, Schwedhelm E, Schulze F, Riekhof D, Böger RH. Pharmacokinetics of oral doses of telmisartan and nisoldipine, given alone and in combination, in patients with essential hypertension. J Clin Pharmacol. 2007;47:295-304. # Corresponding author.

Benndorf RA, Rudolph T, Appel D, Schwedhelm E, Maas R, Schulze F, Silberhorn E, Böger RH. Telmisartan improves insulin sensitivity in non-diabetic patients with essential hypertension. Metabolism. 2006; 55:1159-64.

Hahne AK, Benndorf RA, Frey P, Herzig S. Attitude towards computer-based learning: determinants as revealed by a controlled interventional study. Medical Education. 2005; 39:935-43.

Weil J, Benndorf RA, Fredersdorf S, Griese DP, Eschenhagen T. Regulation of vascular endothelial growth factor expression by adrenoceptor-mediated hypertrophy in rat cardiac myocytes - evidence for a paracrine mechanism. Angiogenesis. 2003; 6:303-9.

Benndorf RA, Böger RH, Ergun S, Steenpass A, Wieland T. Angiotensin II type 2 receptor inhibits vascular endothelial growth factor-induced migration and in vitro tube formation of human endothelial cells. Circ Res. 2003; 93:438-47.

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