Poster 2010
T. Rumpf, J. Köhler, G. Erlenkamp, E. Metzger, A. Eberlin, W. Sippl, R. Schüle, M. Jung.
The clinical candidate Lestaurtinib inhibits the epigenetic kinase PRK1.
1st Max-Plank Epigenetic Meeting
02.-04.12.2010, Freiburg.
M. Pippel, R. Meier, W. Sippl.
ParaDocks. ParaDocks – a Framework for Molecular Docking
6th German Conference on Cheminformatics
07.-09.11.2010, Goslar.
M. Scharfe, B. Maurer, K. Aktories, M. Jung, W. Sippl.
Docking and virtual screening of novel inhibitors for mono-ADP-ribosylating toxins.
6th German Conference on Cheminformatics
07.-09.11.2010, Goslar.
S. Kannan, W. Sippl, M. Zacharias.
Application of BP-Rex MD for loop modeling and refinement of protein structures in explicit solvent
6th German Conference on Cheminformatics
07.-09.11.2010, Goslar.
A. Rohe, C. Philipp, P. Balgarov, C. Göllner, G. Al-Mazaideh, F. Erdmann, W. Sippl, H. Rüttinger, M. Schmidt
Development of a CE based assay for determination of human Myt1 kinase activity.
DPhG-Jahrestagung.
04.10. - 07. 10.2010, Braunschweig.
T. Rumpf, J. Köhler, G. Erlenkamp, E. Metzger, A. Eberlin, W. Sippl, R. Schüle, M. Jung.
Lestaurtinib inhibits the kinase PRK1 in vivo.
DPhG-Jahrestagung.
04.10. - 07. 10.2010, Braunschweig.
T. Rumpf, J. Köhler, G. Erlenkamp, E. Metzger, A. Eberlin, W. Sippl, R. Schüle, M. Jung.
The clinical candidate Lestaurtinib inhibits the epigenetic kinase PRK1. EMBO Conference Series, Chemical Biology 2010
22.-25.09.2010, EMBL Heidelberg.
S. D. Furdas, J. M. Wagner, S. Shekfeh, P. Brown, W. Sippl, M. Jung.
Histone acetyltransferases inhibition by pyridoisothiazolones.
EMBO Conference Series, Chemical Biology 2010
22.-25.09.2010, EMBL Heidelberg
B. Maurer, P. Papatheodorou, C. Schwan, M. Scharfe, W. Sippl, K. Aktories, M. Jung.
Development of an in-vitro-assay for NAD+-dependent enzymes and inhibitor screening.
EMBO Conference Series, Chemical Biology 2010.
22.-25.09.2010, EMBL Heidelberg.
B. Maurer, P. Papatheodorou, C. Schwan, S. Shekfeh, W. Sippl, K. Aktories, M. Jung.
Development of an enzymatic assay for ADP-ribosylating enzymes via the chemical quantitation of the co-substrate NAD.
5th Summer School Medicinal Chemistry.
13.-15. 09.2010, Regensburg.
M. Scharfe, B. Maurer, K. Aktories, M. Jung, W. Sippl.
Docking and virtual screening of novel inhibitors for mono-ADP-ribosylating toxins.
5th Summer School Medicinal Chemistry.
13.-15. 09.2010, Regensburg.
N. Kumawat, S. Kannan, G. Erlenkamp, M. Krug, A. Hilgeroth, W. Sippl
Molecular docking and molecular dynamics simulations of GSK3-kinase inhibitors
5th Summer School Medicinal Chemistry.
13.-15. 09.2010, Regensburg.
S. Shekfeh, S.D. Furdas, M. Jung, W. Sippl.
Docking study and binary classification model of isothiazolones as irreversible inhibitors of the histone acetyltransferase PCAF.
5th Summer School Medicinal Chemistry.
13.-15. 09.2010, Regensburg.
R. Heinke, E.M. Bissinger, A. Spannhoff, M. Jung, W. Sippl
Dapsone derivatives as novel arginine methyltransferase PRMT1 inhibitors.
5th Summer School Medicinal Chemistry.
13.-15. 09.2010, Regensburg.
G. Erlenkamp, W. Sippl
Evaluating the performance of structure- and ligand-based screening methods for kinase inhibitors
5th Summer School Medicinal Chemistry.
13.-15. 09.2010, Regensburg.
M. L. Schmitt, J. Schemies, T. Rumpf, U. Uciechowska, A. Lehotzky, J. Ovadi, W. Sippl, M. Jung.
From modelling to activity – novel sirtuin inhibitors with a thiobarbiturate structure.
EFMC-ISMC
05.09.-09.09.2010, Brussels, Belgium.
R. Lopez, C. Reverdy, S. Conrath, C. Planquette, V. Collura, M. Colombo, W. Sippl, P. Guedat, R. Delansorne, L. Daviet, F. Colland.
Discovery of selective inhibitors of ubiquitin specific proteases
EFMC-ISMC
05.09.-09.09.2010, Brussels, Belgium
M. Pippel, R. Meier, W. Sippl
ParaDocks. ParaDocks – a Framework for Molecular Docking
XXXth European School of Medicinal Chemistry (ESMEC)
04.-09. 07. 2010, Urbino, Italien.
L. Carlino, A. Hauser, M. Jung, W. Sippl
Structure-Based Design of Histone Demethylase LSD1 inhibitors
XXXth European School of Medicinal Chemistry (ESMEC)
04.-09. 07. 2010, Urbino, Italien.
S. D. Furdas, J. M. Wagner, S. Shekfeh, P. Brown, W. Sippl, M. Jung
Pyridoisothiazolones as a novel class of inhibitors of histone acetyltransferase activity: synthesis and biological testing.
XXXth European School of Medicinal Chemistry (ESMEC)
04.-09. 07. 2010, Urbino, Italien.
L. Carlino Luca, A. Hauser, M. Jung, W. Sippl
Structure-Based Design of Histone Demethylase Inhibitors
International Workshop – New Approaches in Drug Design & Discovery
Rauischholzhausen, 22.-25.03.2010
M. Pippel, R. Meier, W. Sippl
ParaDocks – a Framework for Molecular Docking
International Workshop – New Approaches in Drug Design & Discovery
Rauischholzhausen, 22.-25.03.2010
S. Shekfeh, S.D. Furdas, M. Jung, W. Sippl.
Docking study and binary classification model of isothiazolones as irreversible inhibitors of the histone acetyltransferase PCAF.
International Workshop – New Approaches in Drug Design & Discovery
Rauischholzhausen, 22.-25.03.2010