Martin Luther University Halle-Wittenberg

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Publications 2007

I. Bichlmaier, M. Finel, W. Sippl and J. Yli-Kauhaluoma. Stereochemical and Steric Control of the UDP-glucuronosyltransferase-catalyzed Conjugation Reaction. A Rational Approach for the Design of Inhibitors for the Human UGT2B7. Chem. Med. Chem. 2, 1730-40, 2007

A. Spannhoff, R. Machmur, R. Heinke, P. Trojer, I. Bauer, G. Brosch, R. Schüle, W. Hanefeld, W. Sippl and M. Jung. A novel arginine methyltransferase inhibitor with cellular activity. Bioorg. Med. Chem. Lett. 15, 4150-53, 2007

J. Trapp, R. Meier, M. Kassack, W. Sippl and M. Jung. Structure activity studies on suramin analogues as inhibitors of NAD+-dependent histone deacetylases (sirtuins). Chem. Med. Chem. 2, 1419-1431, 2007

B. Schlegel, R. Meier, C. Laggner, D. Schnell, T. Langer, R. Seifert, H. Stark, H.-D. Höltje, and W. Sippl. Generation of a homology model of the human histamine H3 receptor for ligand docking and pharmacophor based screening. J. Comput. Aided-Mol. Design. 21, 437451, 2007

A. Spannhoff, R. Heinke, I. Bauer, P. Trojer, E. Metzger, R. Gust, R. Schüle, G. Brosch, W. Sippl and M. Jung. Target-based approach to inhibitors of histone arginine methyltransferases. J. Med. Chem. 50, 2319-2325, 2007

B. Windshügel, J. Jyrkkarinne, J. Vanamo, A. Poso, P. Honkakoski
and W.Sippl. Comparison of homology models and X-ray structures of the nuclear receptor CAR: Assessing the structural basis of constitutive activity. J. Mol. Graph. Model. 25, 644-657, 2007