Martin Luther University Halle-Wittenberg

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Publications 2013

P.A. Onguéné, F. Ntie-Kang, L. L. Lifongo, J.C. Ndom, W. Sippl and L. Meva’a Mbaze. The potential of anti-malarial compounds derived from African medicinal plants, part I: A pharmacological evaluation of alkaloids and terpenoids. Malaria Journal 2013, 12, 449. doi:10.1186/1475-2875-12-449   

K. Wichapong, A. Nueangaudom, S. Pianwanit, W. Sippl, S. Kokpol. Identification of potential hit compounds for Dengue virus NS2B/NS3 protease inhibitors by combining virtual screening and binding free energy calculations. Trop Biomed. 2013, 3, 388-408. DOI:10.1371/journal.pone.0078085   

F. Ntie-Kang, D. Zofou, S. B Babiaka, R. Meudom, M. Scharfe, L. L Lifongo,
J. A Mbah, L. Meva’a Mbaze, W. Sippl, S. M. N. Efange. AfroDb: A Select Highly Potent and Diverse Natural Product Library from African Medicinal Plants. PlosOne, 2013,8, e78085. doi:10.1371/journal.pone.0078085   

F. Ntie-Kang, L. L. Lifongo, J. A. Mbah,  L. C. Owono Owono, E. Megnassan, L. Meva’a Mbaze, P. N. Judson, W. Sippl and S. M. N. Efange. In silico drug metabolism and pharmacokinetic profiles of natural products from medicinal plants in the Congo basin. In silico Pharmacology, 2013, 1:12. doi:10.1186/2193-9616-1-12   

F. Ntie-Kang, J. A. Mbah, L. L. Lifongo, L. C. Owono Owono, E. Megnassan,
L. Meva’a Mbaze, P. N. Judson, W. Sippl and S. M. N. Efange. Assessing the pharmacokinetic profile of the CamMedNP natural products database: An in silico approach. Org Med Chem Letters, 2013 3, 10. doi:10.1186/2191-2858-3-10   

M. Marek, S. Kannan, A.T. Hauser, M.M. Mourao, S. Caby, V. Cura, D.A. Stolfa, K. Schmidtkunz, J. Lancelot, L. Andrade, J.P.Renaud, G. Oliveira, W. Sippl, M. Jung, J. Cavarelli, R. J. Pierce, C. Romier. Structural Basis for the Inhibition of histone deacetylase 8 ( HDAC8), a Key Epigenetic Player in the Blood Fluke Schistosoma mansoni. Plos Pathogens, 2013, 9, e1003645. doi:10.1371/journal.ppat.1003645   

M L. Schmitt, A.T. Hauser, L. Carlino, M. Pippel,  E. Metzger, D. Willmann ,
T. Yiu, M. Barton, R. Schüle, W. Sippl, and M. Jung. Propargylamines as inhibitors of lysine specific demethylase 1with cellular activity. J. Med. Chem. 2013, 56, 7334-7342. doi:10.1021/jm400792m   

Zofou D, Ntie-Kang F, Sippl W, Efange SM. Bioactive natural products derived from the Central African flora against neglected tropical diseases and HIV. Nat Prod Rep. 2013, 30, 1098-120. doi:10.1039/c3np70030e.   

Ntie-Kang F, Lifongo LL, Mbaze LM, Ekwelle N, Owono Owono LC, Megnassan E, Judson PN, Sippl W, Efange SM. Cameroonian medicinal plants: a bioactivity versus ethnobotanical survey and chemotaxonomic classification. BMC Complement Altern Med. 2013, 13:147. doi:10.1186/1472-6882-13-147.   

F. Ntie-Kang, J.A. Mbah, L.M. Mbaze, L.L. Lifongo, M. Scharfe, J.N. Hanna,
F. Cho-Ngwa, P.A. Onguéné, L.C. Owono, E. Megnassan, W. Sippl,
S. M. Efange. CamMedNP: Building the Cameroonian 3D structural natural products database for virtual screening. BMC Complement Altern Med. 2013, 13:88. doi:10.1186/1472-6882-13-88   

Heinz A, Ruttkies CK, Jahreis G, Schräder CU, Wichapong K, Sippl W,
Keeley FW, Neubert RH, Schmelzer CE. In vitro cross-linking of elastin peptides and molecular characterization of the resultant biomaterials. Biochim Biophys Acta 2013, 1830, 2994-3004. doi:10.1016/j.bbagen.2013.01.014   

A. Rohe, C. Göllner, K. Wichapong, F. Erdmann, G. M. A. Al-Mazaideh, W. Sippl and M. Schmidt. Evaluation of potential Myt1 kinase inhibitors by TR-FRET based binding assay. Eur. J. Med. Chem, 2013, 61, 41-8. doi:10.1016/j.ejmech.2012.06.007